منابع مشابه
Roles of Stem Cells in the Treatment of Alzheimer’s Disease
Introduction: Alzheimer disease (AD), known to be a leading cause of dementia that causes heavy social and financial burdens worldwide, characterized by progressive loss of neurons and synaptic connectivity after depositions of amyloid-β (Aβ) protein.AD manifests as an impaired ability to comprehend or use words, poor coordination and gait, and impaired executive functions in the realms of plan...
متن کاملP 141: Mesenchymal Stem Cells as Treatment in Neuroinflammatory Disease
Mesenchymal stem cells can be obtained from deferent tissues like adipose tissue, umbilical cord, placenta, skin, bone marrow, etc. These cells have regulatory effects on all types of immune cells such as dendritic cell, natural killers and lymphocytes. Mesenchymal stem cells induce inhibitory phenotypes of Antigen Presenting Cells (APCs) following their activity. They also change T cells pheno...
متن کاملImprovement in Signs of Parkinson's Disease in Rats Following Transplantation of Embryonic Stem Cells
Purpose: Parkinson's disease is a degenerative disease produced by the death of dopaminergic neurons, and the response to current treatments is varied. It is important to develop a model for the evaluation of ES cells as an alternative model for treatment. Materials and Methods: The model for PD was developed in rats. First, ES cells were transplanted into experimental models in three groups: ...
متن کاملMesenchymal stem cells that located in the electromagnetic fields improves rat model of Parkinson's disease
Objective(s): The main characteristic of mesenchymal stem cells (MSCs) is their ability to produce other cell types. Electromagnetic field (EMF) stimulates differentiation of MSCs into other cells. In this study, we investigated whether EMF can effect on the differentiation of MSCs into dopaminergic (DA) neurons. Materials and Methods: An EMF with a frequency of 50 Hz and two intensities of 40 ...
متن کاملG-CSF for mobilizing transplanted bone marrow stem cells in rat model of Parkinson's disease
Objective(s): Granulocyte-colony stimulating factor (G-CSF) is used in clinical practice for the treatment of neutropenia and to stimulate generation of hematopoietic stem cells in bone marrow donors. In the present study, the ability of G-CSF in mobilizing exogenous bone marrow stem cells (BMSCs) from peripheral blood into the brain was tested. We for the first time injected a small amount of ...
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ژورنال
عنوان ژورنال: Stem Cells International
سال: 2012
ISSN: 1687-966X,1687-9678
DOI: 10.1155/2012/565083